Autoimmune Diseases

Autoimmunity is the failure of an organism to recognize its own constituent parts (down to the sub-molecular levels) as self, which results in an immune response against its own cells and tissues. More than 80 autoimmune diseases have been described to date. Some, such as type 1 diabetes, attack specific organs, while others, such as systemic lupus erythematosus (SLE), involve multiple organs. Although many autoimmune diseases are rare, collectively they affect approximately 5 to 8 percent of the U.S. population. A disproportionate number of people with autoimmune disorders are women. For unknown reasons, the prevalence of autoimmune diseases is increasing.

Company Product Phase  
Halozyme Therapeutics Inc Gammagard M Autoimmune Diseases
Halozyme Therapeutics Inc Gammagard Liquid with rHuPH20 III Autoimmune Diseases
Limerick BioPharma, Inc. (formerly Limerick NeuroSciences, Inc.) III LIM5310 Autoimmune Diseases

Carpal Tunnel Syndrome

Carpal tunnel syndrome is a painful progressive condition caused by compression of a key nerve in the wrist. It occurs when the median nerve, which runs from the forearm into the hand, becomes pressed or squeezed at the wrist. The risk of developing carpal tunnel syndrome is especially common in those performing assembly line work.

Company Product Phase  
Teikoku Pharma USA Inc Carpal tunnel tape II Carpal Tunnel Syndrome

Crohn’s disease

Crohn's disease is a chronic inflammatory disease of the intestines. It primarily causes ulcerations (breaks in the lining) of the small and large intestines, but can affect the digestive system anywhere from the mouth to the anus. Crohn’s disease also contributes to Irritable Bowel Syndrome. Crohn’s may also cause other bowel abnormalities as well as affect other organs, contributing to skin rashes, fistulas, liver inflammation and arthritis. It is most common in people between the ages of 20 and 30. Both men and women can have Crohn’s disease.

Company Product Phase  
Prometheus Laboratories Inc Entocort EC M Crohn's Disease
Ocera Therapeutics Inc AST120 III Crohn's Disease
Genentech, Inc. MLN0002 III Crohn's Disease
ChemoCentryx Inc Traficet-EN III Crohn's Disease
Facet Biotech Corporation Nuvion II Crohn's Disease
Genentech, Inc. Somatropin II Crohn's Disease