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Non-Hodgkin’s Lymphoma
Non-Hodgkin lymphomas can occur at any age and are often marked by enlarged lymph nodes, fever, and weight loss. There are many different types of non-Hodgkin lymphoma, which can be divided into aggressive (fast-growing) and indolent (slow-growing) types and can be classified as either B-cell or T-cell non-Hodgkin lymphoma. B-cell non-Hodgkin lymphomas include Burkitt lymphoma, diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell non-Hodgkin lymphomas include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas related to lymphoproliferative disorders following bone marrow or stem cell transplantation are usually B-cell non-Hodgkin lymphomas. Prognosis and treatment depend on the stage and type of disease. Also called NHL. According to the National Cancer Institute, there were 66,120 new cases in 2008.
| Company | Product | Phase | |
| Genentech Inc | Rituxan | M | Non-Hodgkin Lymphoma |
| Genentech Inc | Rituxan with CHOP | M | Non-Hodgkin Lymphoma |
| Genentech Inc | Rituxan with CVP | M | Non-Hodgkin Lymphoma |
| Spectrum Pharmaceuticals Inc | Zevalin | M | Non-Hodgkin Lymphoma |
| Genentech, Inc. | MabThera with Avastin | III | Non-Hodgkin Lymphoma |
| Genitope Corp | MyVax personalized immunotherapy | III | Non-Hodgkin Lymphoma |
| Genitope Corp | MyVax personalized immunotherapy with Rituxan | III | Non-Hodgkin Lymphoma |
| Genentech Inc | Rituxan with Avastin | III | Non-Hodgkin Lymphoma |
| Genentech, Inc. | Rituxan with Chemotherapy | III | Non-Hodgkin Lymphoma |
| Spectrum Pharmaceuticals Inc | Zevalin with Rituxan | III | Non-Hodgkin Lymphoma |
| Geron Corporation | GRN163L | II | Lymphoma |
| XOMA Ltd | HCD122 | II | Lymphoma |
| Pharmacyclics Inc | PCI24781 | II | Lymphoma |
| Spectrum Pharmaceuticals Inc | Zevalin with R-FND | II | Lymphoma |
| Dynavax Technologies Corp | 1018 ISS with Rituxan | II | Non-Hodgkin Lymphoma |
| Genentech Inc | Apomab with Rituxan | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | Avastin with Rituxan | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | CC5103 with Rituximab | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | Chemotherapy, Rituxan with Pegfilgrastim, Rituxan | II | Non-Hodgkin Lymphoma |
| Amgen Inc | Chemotherapy, Rituxan with Pegfilgrastim, Rituxan | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | GA101 | II | Non-Hodgkin Lymphoma |
| Hana Biosciences Inc | Marqibo | II | Non-Hodgkin Lymphoma |
| SuperGen Inc | Nipent with Cytoxan and Rituxan | II | Non-Hodgkin Lymphoma |
| Amgen Inc | rhApo2L/TRAIL with Rituxan | II | Non-Hodgkin Lymphoma |
| Genentech Inc | rhApo2L/TRAIL with Rituxan | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | R-ICE Chemotherapy with SGN40 (Second Line Therapy) | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | Rituxan with Fludarabine | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | Rituxan with HCVAD | II | Non-Hodgkin Lymphoma |
| Cytokinetics Inc | SB743921 | II | Non-Hodgkin Lymphoma |
| Genentech, Inc. | SGN40 | II | Non-Hodgkin Lymphoma |
| Pharmacyclics Inc | Xcytrin | II | Non-Hodgkin Lymphoma |
| Spectrum Pharmaceuticals Inc | Zevalin with BEAM | II | Non-Hodgkin Lymphoma |
| Spectrum Pharmaceuticals Inc | Zevalin with Motexafin gadolinium | II | Non-Hodgkin Lymphoma |
| Novartis AG | Proleukin (aldesleukin) with Rituximab | II | Non-Hodgkin's Lymphoma |