Chemotherapy- and Radiotherapy-Induced Side Effects

Cancer is often treated with a chemotherapy and/or radiotherapy. Radiation and chemotherapy, unfortunately, often bring with them a variety of side effects ranging from hair loss and appetite changes to decreased general immune function. Current treatments and concomitant supportive care medications may lessen the severity and occurrences of these effects.

Company Product Phase  
BioPro Pharmaceutical, Inc. Fentanyl PA Chemotherapy-induced Side Effects
Amgen Inc Prolia PA Chemotherapy-induced Side Effects
Pharmagenesis Inc Injectable Astragalus Polysaccharide M Chemotherapy-induced Side Effects
Watson Pharmaceuticals Inc Fentanyl Citrate M Chemotherapy-induced Side Effects
Novartis AG Cardioxane (dexrazoxane) M Chemotherapy-induced Side Effects
Valeant Pharmaceuticals International Cesamet M Chemotherapy-induced Side Effects
Watson Pharmaceuticals Inc Dronabinol M Chemotherapy-induced Side Effects
Spectrum Pharmaceuticals Inc Fusilev M Chemotherapy-induced Side Effects
Spectrum Pharmaceuticals Inc Fusilev M Chemotherapy-induced Side Effects
Amgen Inc Neupogen M Chemotherapy-induced Side Effects
Amdl Inc Ondansetron hydrochloride M Chemotherapy-induced Side Effects
AP Pharma Inc APF530 II Chemotherapy-induced Side Effects
Pharmagenesis Inc Xuebao II Chemotherapy-induced Side Effects
Applied Protein Sciences, LLC AP001 II Chemotherapy-induced Side Effects
Maxygen Inc MaxyG34 II Chemotherapy-induced Side Effects
Amgen Inc Nplate II Chemotherapy-induced Side Effects
Ligand Pharmaceuticals Inc Promacta II Chemotherapy-induced Side Effects
SciClone Pharmaceuticals Inc SCV07 II Chemotherapy-induced Side Effects
Telik Inc Telintra II Chemotherapy-induced Side Effects

Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) occurs later in life and is a malignancy of the lymphocyte. CLL cells grow uncontrollably in the bone marrow, causing an increased concentration of those cells in the blood. The CLL cells do not affect normal blood cell production as is the case in other forms of leukemia, lessening the symptoms in the early stages of the disease. According to the Leukemia-Lymphoma Society, nearly 10,020 people are diagnosed with chronic lymphocytic leukemia in the U.S. each year, most of whom are over 50 years old at the time of diagnosis.

Company Product Phase  
SuperGen Inc Nipent with Cytoxan and Rituxan PM Chronic Lymphocytic Leukemia
Genentech Inc Rituxan with chemotherapy III Chronic Lymphocytic Leukemia
Genentech Inc ABT263 II Chronic Lymphocytic Leukemia
Genentech Inc Anti-CD20 (III Generation) II Chronic Lymphocytic Leukemia
Cylene Pharmaceuticals, Inc. CX3543 II Chronic Lymphocytic Leukemia
Genentech, Inc. GA101 II Chronic Lymphocytic Leukemia
Geron Corp GRN163L II Chronic Lymphocytic Leukemia
Tragen Pharmaceuticals ISF154 II Chronic Lymphocytic Leukemia
Facet Biotech Corporation TRU016 II Chronic Lymphocytic Leukemia
Pharmacyclics Inc Xcytrin II Chronic Lymphocytic Leukemia

Chronic Myelogenous Leukemia

Chronic myelogenous leukemia, also called CML, is a disease in which the bone marrow makes too many white blood cells. CML is a slowly progressing blood and bone marrow disease that usually occurs during or after middle age, and rarely occurs in children. Normally, the bone marrow makes blood stem cells (immature cells) that develop into mature blood cells over time. A blood stem cell may become a myeloid stem cell or a lymphoid stem cell. The lymphoid stem cell develops into a white blood cell. The National Cancer Institute estimates that about 4,830 new cases are diagnosed each year in the U.S.