Colon Cancer/ Colorectal Cancer

Colorectal cancer starts either in the large intestine (colon) or in the rectum (end of the colon). The most common form is called adenocarcinoma of the colon. Research shows that most colorectal cancers start as benign polyps, which over a period of many years develop into cancers. Other factors that contribute are ulcerative colitis, a family history of colon cancer and a high-meat, high-fat, low-fiber diet. The National Cancer Institute estimated 148,810 new cases of colon and rectal cancer in 2008.

Company Product Phase  
Spectrum Pharmaceuticals Inc Fusilev with 5-Fluorouracil-based chemotherapy PA Colorectal Cancer
Genentech Inc Avastin with Fluorouracil Based Chemotherapy M Colorectal Cancer
Amgen Inc Vectibix M Colorectal Cancer
Genentech, Inc. Avastin with XELOX or FOLFOX III Colorectal Cancer
Genentech, Inc. Xelox III Colorectal Cancer
Genentech, Inc. Avastin (Second Line Therapy) III Colorectal Cancer
Genentech, Inc. Avastin with Chemotherapy and Tarceva III Colorectal Cancer
Amgen Inc Vectibix with FOLFIRI (Second Line Therapy) III Colorectal Cancer
Amgen Inc Vectibix with FOLFOX III Colorectal Cancer
Genomic Health Inc Colon Cancer Diagnostic II Colorectal Cancer
Jennerex Biotherapeutics, Inc. JX594 II Colorectal Cancer
Genentech Inc ABT869 II Colorectal Cancer
Poniard Pharmaceuticals Inc AMD473 with 5-fluorouracil and Leucovorin (First Line Therapy) II Colorectal Cancer
Amgen Inc AMG102 with Panitumumab II Colorectal Cancer
Amgen Inc AMG386 with FOLFIRI II Colorectal Cancer
Amgen Inc AMG479 with Panitumumab II Colorectal Cancer
Amgen Inc AMG655 with mFOLFOX6 and Bevacizumab (First-Line Therapy) II Colorectal Cancer
Amgen Inc AMG655 with Panitumumab II Colorectal Cancer
Actis Biologics, Inc. Angiozyme II Colorectal Cancer
Genentech, Inc. Avastin with Capecitabine and Oxaliplatin (First Line Therapy) II Colorectal Cancer
Genentech, Inc. Avastin with RAD001 II Colorectal Cancer
Genentech, Inc. Avastin with Tarceva, FOLFOX II Colorectal Cancer
Genentech, Inc. Avastin with Xeloda II Colorectal Cancer
ACT Biotech, Inc. BAY579352 (Second Line) II Colorectal Cancer
Genentech, Inc. GDC0449 with Bevacizumab and Chemotherapy (First Line Therapy) II Colorectal Cancer
Onyx Pharmaceuticals Inc w/ Bayer Healthcare Pharmaceuticals Nexavar II Colorectal Cancer
Onyx Pharmaceuticals Inc Nexavar with mFOLFOX6 II Colorectal Cancer
Nektar Therapeutics NKTR102 II Colorectal Cancer
Nektar Therapeutics NKTR102 with Cetuximab (Second Line Therapy) II Colorectal Cancer
SuperGen Inc Orathecin II Colorectal Cancer
HERMES Biosciences PEP02 with 5-Flourouracil and leucovorin II Colorectal Cancer
Cytokinetics Inc SB715992 (Second Line Therapy) II Colorectal Cancer
Genentech, Inc. Tarceva with Chemotherapy II Colorectal Cancer
Genentech, Inc. Tarceva with Oxaliplatin and Capecitabine II Colorectal Cancer
Telik Inc Telcyta II Colorectal Cancer
Amgen Inc Vectibix with FOLFIRI (First Line Therapy) II Colorectal Cancer

Esophageal Cancer

Esophageal cancer forms in tissues lining the esophagus, the muscular tube through which food passes from the throat to the stomach. Two types of esophageal cancer are squamous cell carcinoma (cancer that begins in flat cells lining the esophagus) and adenocarcinoma (cancer that begins in cells that make and release mucus and other fluids). Very small tumors in the esophagus usually do not cause symptoms. As a tumor grows, the most common symptom is difficulty in swallowing. The National Cancer Institute estimated 16,470 new cases in 2008.

Company Product Phase  
Genentech, Inc. Avastin with Chemoradiation II Esophageal Cancer
Genentech, Inc. Avastin with Modified DCF II Esophageal Cancer
Genentech, Inc. Avastin, Tarceva with Chemotherapy, Radiotherapy II Esophageal Cancer