Gastrointestinal Cancer

Gastrointestinal cancer refers to cancer which forms within the gastrointestinal tract, somewhere in the esophagus, stomach, liver, biliary system, pancreas, bowels, or anus. Several risk factors for developing gastrointestinal cancer have been identified. The frequency of gastrointestinal tumors increases with each decade of life and these tumors occur somewhat more frequently in men than in women. Persons of Asian, Pacific Islander, Hispanic and African American descent have a statistically higher chance of developing the cancer compared to non-Hispanic white Americans. Additionally, eating smoked, salted or pickled foods may lead to an increased risk, whereas eating fresh fruits and vegetables lowers the risk. Also, as with several other cancers, cigarette smokers tend to have increased rates of stomach cancers.

Company Product Phase  
Genentech, Inc. Avastin III Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with Xeloda and Cisplatin (First Line Therapy) III Gastrointestinal (Stomach) Cancer
Amgen Inc AMG102 with Epirubicin, Cisplatin and Capecitabine (First Line Therapy) II Gastrointestinal (Stomach) Cancer
Amgen Inc AMG386 II Gastrointestinal (Stomach) Cancer
Amgen Inc AMG706 II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with Capecitabine and Carboplatin II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with Capecitabine, Oxaliplatin and Radiation Therapy II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with Docetaxel, Cisplatin and Irinotecan II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with FOLFOX II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with Taxotere II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Avastin with Xelox II Gastrointestinal (Stomach) Cancer
ACT Biotech, Inc. BAY579352 (First Line) II Gastrointestinal (Stomach) Cancer
ACT Biotech, Inc. BAY579352 (Second Line) II Gastrointestinal (Stomach) Cancer
Regulon, Inc Lipoplatin with Radiotherapy, 5-Fluorouracil II Gastrointestinal (Stomach) Cancer
Regulon, Inc Lipoxal II Gastrointestinal (Stomach) Cancer
Onyx Pharmaceuticals Inc Nexavar II Gastrointestinal (Stomach) Cancer
Onyx Pharmaceuticals Inc Nexavar with Docetaxel and Cisplatin II Gastrointestinal (Stomach) Cancer
SuperGen Inc Orathecin II Gastrointestinal (Stomach) Cancer
HERMES Biosciences PEP02 II Gastrointestinal (Stomach) Cancer
Genentech, Inc. Tarceva with FOLFOX6 II Gastrointestinal (Stomach) Cancer
Exelixis Inc XL880 II Gastrointestinal (Stomach) Cancer

Head and Neck Cancer

Most head and neck cancers begin in the mucous linings in the head and neck, such as the sinuses, mouth and larynx. Symptoms of such a cancer usually include a lump or sore that does not heal, a persistent sore throat, difficulty swallowing and a change of hoarseness in the voice. As many as 90 percent of head and neck cancers arise after prolonged exposure to specific factors including tobacco (cigarettes, cigars, chewing tobacco or snuff) and/or alcoholic beverages. Prolonged exposure to sunlight is linked with cancer of the lip and is also a major cause of skin cancer. There were about 40,490 new cases in 2006.

Company Product Phase  
Genentech, Inc. Avastin III Head and Neck Cancer
Regulon, Inc Lipoplatin with fluorouracil III Head and Neck Cancer
Genentech, Inc. Tarceva III Head and Neck Cancer
Amgen Inc Vectibix III Head and Neck Cancer
Abraxis BioScience, Inc. Abraxane with Carboplatin, Erbitux and IMRT II Head and Neck Cancer
Genentech, Inc. Alimta with Avastin II Head and Neck Cancer
Genentech, Inc. Avastin with Tarceva II Head and Neck Cancer
Genentech, Inc. Avastin with Tarceva and Radiation II Head and Neck Cancer
Genentech, Inc. Avastin with Tarceva, Chemotherapy and Radiation Therapy II Head and Neck Cancer
Regulon, Inc Lipoplatin with Radiation II Head and Neck Cancer
Onyx Pharmaceuticals Inc Nexavar with Carboplatin and Paclitaxel II Head and Neck Cancer
Cytokinetics Inc SB715992 (First or Second Line Therapy) II Head and Neck Cancer
Genentech, Inc. Tarceva II Head and Neck Cancer
Genentech, Inc. Tarceva with Bevacizumab or Sulindac II Head and Neck Cancer
Genentech, Inc. Tarceva with Docetaxel and Cisplatin II Head and Neck Cancer
Genentech, Inc. Tarceva with RADPLAT II Head and Neck Cancer
Exelixis Inc XL880 II Head and Neck Cancer