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Hematological Malignancies
Hematological malignancies are the types of cancer that affect blood, bone marrow and lymph nodes. As the three are intimately connected through the immune system, a disease affecting one of the three will often affect the others as well: although lymphoma is technically a disease of the lymph nodes, it often spreads to the bone marrow, affecting the blood and occasionally producing a paraprotein.
| Company | Product | Phase | |
| Amgen Inc | Aranesp with Venofer | III | Hematological Malignancies |
| Amgen Inc | StemEx | III | Hematological Malignancies |
| Gilead Sciences Inc | GS9219 | II | Hematological Malignancies |
| SuperGen Inc | Myelosuppressive Regimen with Pentostatin and Low-Dose Total Body | II | Hematological Malignancies |
| TargeGen Inc | TG101348 | II | Hematological Malignancies |
Hodgkin's Lymphoma
Cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell, Hodgkin’s Lymphoma is categorized into two types. Hodgkin lymphoma are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. The National Cancer Institute estimated 8,220 new cases in 2008.
| Company | Product | Phase | |
| Genentech, Inc. | Avastin with ABVD | II | Hodgkin Lymphoma |
| Genentech, Inc. | Rituxan with ABVD | II | Hodgkin Lymphoma |
| Cytokinetics Inc | SB743921 | II | Hodgkin Lymphoma |
| Genentech, Inc. | TNX650 | II | Hodgkin Lymphoma |
Kidney Cancer
Kidney cancer in adults and children are different and distinct. Kidney cancer includes renal cell carcinoma (cancer that forms in the lining of very small tubes in the kidney that filter the blood and remove waste products) and renal pelvis carcinoma (cancer that forms in the center of the kidney where urine collects). It also includes Wilms tumor, which is a type of kidney cancer that usually develops in children under the age of 5. According to the National Cancer Institute, there were about 54,390 new cases in 2008.
| Company | Product | Phase | |
| Johnson & Johnson | Doxil / Caelyx (pegylated liposomal doxorubicin hydrochloride) | M | Kaposi Sarcoma |
| Onyx Pharmaceuticals Inc w/ Bayer Healthcare Pharmaceuticals | Nexavar | M | Kidney Cancer |
| Novartis AG | Proleukin (aldesleukin) | M | Kidney Cancer |
| Onyx Pharmaceuticals Inc w/ Bayer Healthcare Pharmaceuticals | Nexavar with Sunitinib | III | Kidney Cancer |
| Genentech Inc | ABT869 | II | Kidney Cancer |
| Amgen Inc | AMG102 | II | Kidney Cancer |
| Amgen Inc | AMG386 | II | Kidney Cancer |
| Amgen Inc | AMG386 with Sunitinib | II | Kidney Cancer |
| Genentech, Inc. | Avastin | II | Kidney Cancer |
| Genentech, Inc. | Avastin with Gemcitabine and Capecitabine | II | Kidney Cancer |
| Genentech, Inc. | Avastin with RAD001 | II | Kidney Cancer |
| Genentech, Inc. | Avastin with Temsirolimus | II | Kidney Cancer |
| Genentech, Inc. | Avastin, Tarceva with Gleevec | II | Kidney Cancer |
| Onyx Pharmaceuticals Inc | Nexavar with Gemcitabine and Capecitabine | II | Kidney Cancer |
| Onyx Pharmaceuticals Inc | Nexavar with Interferon | II | Kidney Cancer |
| Cytokinetics Inc | SB715992 (Second Line Therapy) | II | Kidney Cancer |
| Genentech, Inc. | Tarceva with Rapamune | II | Kidney Cancer |
| Amgen Inc | Vectibix | II | Kidney Cancer |
| VasGene Therapeutics Inc | Veglin with IL-2 | II | Kidney Cancer |
| Pharmacyclics Inc | Xcytrin | II | Kidney Cancer |
| Exelixis Inc | XL880 | II | Kidney Cancer |
| SuperGen Inc | Orathecin | II | Sarcoma |
| Pharmacyclics Inc | PCI24781 with Doxorubicin | II | Sarcoma |
| Threshold Pharmaceuticals Inc | TH302 with Doxorubicin | II | Sarcoma |
| Genentech Inc | Avastin with interferon alfa-2a | A | Kidney Cancer |
