Hematological Malignancies

Hematological malignancies are the types of cancer that affect blood, bone marrow and lymph nodes. As the three are intimately connected through the immune system, a disease affecting one of the three will often affect the others as well: although lymphoma is technically a disease of the lymph nodes, it often spreads to the bone marrow, affecting the blood and occasionally producing a paraprotein.

Company Product Phase  
Amgen Inc Aranesp with Venofer III Hematological Malignancies
Amgen Inc StemEx III Hematological Malignancies
Gilead Sciences Inc GS9219 II Hematological Malignancies
SuperGen Inc Myelosuppressive Regimen with Pentostatin and Low-Dose Total Body II Hematological Malignancies
TargeGen Inc TG101348 II Hematological Malignancies

Hodgkin's Lymphoma

Cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell, Hodgkin’s Lymphoma is categorized into two types. Hodgkin lymphoma are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. The National Cancer Institute estimated 8,220 new cases in 2008.

Company Product Phase  
Genentech, Inc. Avastin with ABVD II Hodgkin Lymphoma
Genentech, Inc. Rituxan with ABVD II Hodgkin Lymphoma
Cytokinetics Inc SB743921 II Hodgkin Lymphoma
Genentech, Inc. TNX650 II Hodgkin Lymphoma

Kidney Cancer

Kidney cancer in adults and children are different and distinct. Kidney cancer includes renal cell carcinoma (cancer that forms in the lining of very small tubes in the kidney that filter the blood and remove waste products) and renal pelvis carcinoma (cancer that forms in the center of the kidney where urine collects). It also includes Wilms tumor, which is a type of kidney cancer that usually develops in children under the age of 5. According to the National Cancer Institute, there were about 54,390 new cases in 2008.

Company Product Phase  
Johnson & Johnson Doxil / Caelyx (pegylated liposomal doxorubicin hydrochloride) M Kaposi Sarcoma
Onyx Pharmaceuticals Inc w/ Bayer Healthcare Pharmaceuticals Nexavar M Kidney Cancer
Novartis AG Proleukin (aldesleukin) M Kidney Cancer
Onyx Pharmaceuticals Inc w/ Bayer Healthcare Pharmaceuticals Nexavar with Sunitinib III Kidney Cancer
Genentech Inc ABT869 II Kidney Cancer
Amgen Inc AMG102 II Kidney Cancer
Amgen Inc AMG386 II Kidney Cancer
Amgen Inc AMG386 with Sunitinib II Kidney Cancer
Genentech, Inc. Avastin II Kidney Cancer
Genentech, Inc. Avastin with Gemcitabine and Capecitabine II Kidney Cancer
Genentech, Inc. Avastin with RAD001 II Kidney Cancer
Genentech, Inc. Avastin with Temsirolimus II Kidney Cancer
Genentech, Inc. Avastin, Tarceva with Gleevec II Kidney Cancer
Onyx Pharmaceuticals Inc Nexavar with Gemcitabine and Capecitabine II Kidney Cancer
Onyx Pharmaceuticals Inc Nexavar with Interferon II Kidney Cancer
Cytokinetics Inc SB715992 (Second Line Therapy) II Kidney Cancer
Genentech, Inc. Tarceva with Rapamune II Kidney Cancer
Amgen Inc Vectibix II Kidney Cancer
VasGene Therapeutics Inc Veglin with IL-2 II Kidney Cancer
Pharmacyclics Inc Xcytrin II Kidney Cancer
Exelixis Inc XL880 II Kidney Cancer
SuperGen Inc Orathecin II Sarcoma
Pharmacyclics Inc PCI24781 with Doxorubicin II Sarcoma
Threshold Pharmaceuticals Inc TH302 with Doxorubicin II Sarcoma
Genentech Inc Avastin with interferon alfa-2a A Kidney Cancer