Atrial Fibrillation

Atrial fibrillation (AF) is an irregular heart rhythm, or arrhythmia, that starts in the upper parts of the heart. Normally, the heart beats in a strong, steady rhythm. AF occurs when rapid, disorganized electrical signals in the heart’s two upper chambers, called the atria, cause them to contract very fast and irregularly (this is called fibrillation). As a result, blood pools in the atria and isn’t pumped completely into the heart’s two lower chambers, called the ventricles. When this happens, the heart’s upper and lower chambers don’t work together as they should.Atrial fibrillation can also lead to heart failure or heart attack.

Company Product Phase  
Watson Pharmaceuticals Inc Propafenone hydrochloride M Atrial Fibrillation
Watson Pharmaceuticals Inc Quinidine gluconate ER WATSON M Atrial Fibrillation
Amylin Pharmaceuticals Inc Rythmol SR M Atrial Fibrillation
ARYx Therapeutics ATI2042 II Atrial Fibrillation
Gilead Sciences Inc CVT510 II Atrial Fibrillation

Blood Clot

Blood that has been converted from a liquid to a solid state inside the circulatory system poses a potential danger to the person. Stationary, a thrombus, or more simply a blood clot, is inactive. But if it moves from that location through the bloodstream it is referred to as an embolus and can potentially decrease or cut off the flow of blood to tissue, resulting in death, stroke or heart attack.

Company Product Phase  
Genentech Inc Cathflo Activase M Blood Clot
Valeant Pharmaceuticals International Aclotin M Thromboembolism
Impax Laboratories Inc Dipyridamole M Thromboembolism
Valeant Pharmaceuticals International Acenokumarol M Thrombosis
Valeant Pharmaceuticals International Clivarine M Thrombosis
Andrx Enoxaparin Sodium M Thrombosis
Valeant Pharmaceuticals International Syncumar M Thrombosis
ATI5923 III Thrombosis
ARYx Therapeutics, Inc. ATI5923 III Thrombosis
Portola Pharmaceuticals, Inc. PRT054021 II Thromboembolism
Portola Pharmaceuticals Inc PRT054021 II Thrombosis
Genentech, Inc. Rituxan II Thrombosis
Cepheid Xpert(R) HemosIL(R) FII & FV A Thrombosis

Cardiac Surgeries

One of many forms of bypass surgery that can create new routes around narrowed and blocked coronary arteries, cardiac surgeries permit increased blood flow to deliver oxygen and nutrients to the heart muscle. These surgeries are an option for selected groups of patients with significant narrowings and blockages of the heart arteries. The bypass graft for a Cardiopulmonary Bypass Graft (CABG) can be a vein from the leg or an inner chest-wall artery. CABG surgery is one of the most commonly performed major operations. Coronary artery disease develops because of hardening of the arteries that supply blood to the heart muscle.

Cardiovascular Diseases

Cardiovascular diseases are any such ailments that affect the heart or blood vessels. Cardiovascular diseases include arteriosclerosis, coronary artery disease, heart valve disease, arrhythmia, heart failure, hypertension, orthostatic hypotension, shock, endocarditis, diseases of the aorta and its branches, disorders of the peripheral vascular system and congenital heart disease.

Company Product Phase  
AXM Pharma Inc Atenolol M Cardiovascular Diseases
Watson Pharmaceuticals Inc Cartia XT M Cardiovascular Diseases
Watson Pharmaceuticals Inc Co-Enzyme Q10 M Cardiovascular Diseases
Watson Pharmaceuticals Inc Diltia XT M Cardiovascular Diseases
Watson Pharmaceuticals Inc Metoprolol succinate ER M Cardiovascular Diseases
Watson Pharmaceuticals Inc Metoprolol tartrate M Cardiovascular Diseases
Watson Pharmaceuticals Inc Taztia XT M Cardiovascular Diseases
Watson Pharmaceuticals Inc Verapamil hydrochloride M Cardiovascular Diseases
Scios Inc Natrecor M Congestive Heart Failure
Amgen Inc III Sensipar Cardiovascular Diseases
Corthera Inc. Relaxin III Congestive Heart Failure
CytRx Corporation BRX235 II Cardiovascular Diseases
CytRx Corp Iroxanadine II Cardiovascular Diseases
XOMA Ltd Neuprex II Cardiovascular Diseases
VIA Pharmaceuticals Inc VIA2291 II Cardiovascular Diseases
Gilead Sciences Inc Adentri II Congestive Heart Failure
Amgen Inc AMG423 II Congestive Heart Failure
Nile Therapeutics Inc CD-NP II Congestive Heart Failure
Amgen Inc CK1827452 II Congestive Heart Failure
Cytokinetics Inc CK1827452 II Congestive Heart Failure
Capricor Inc. CPI 005 II Congestive Heart Failure
Celladon Corporation Mydicar II Congestive Heart Failure
Neurocrine Biosciences Inc NBI69734 II Congestive Heart Failure
Anthera Pharmaceuticals, Inc. A002 II Coronary Artery Disease
Medlogics Device Corporation Cobra II Coronary Artery Disease
BioMarin Pharmaceutical Inc 6RBH4 II Peripheral Arterial Disease
Medlogics Device Corporation Drug Q A Coronary Artery Disease