Multiple Sclerosis (MS)

Multiple Sclerosis is a chronic disorder in which damage occurs to the protective tissue, known as myelin, surrounding the nerve fibers of the central nervous system. With MS, a person’s immune system malfunctions and starts attacking the body’s own tissues. In this case, the myelin sheaths are affected. Myelin protects the nerves and is necessary for their proper function. As the disease progresses and myelin is destroyed, the nerve impulses are interrupted and the symptoms of MS occur.

The 400,000 Americans with MS are different in the extent to which they are affected. There are four clinical courses of the disease which range from occasional flare ups to the constant worsening of symptoms and combinations of the two.

Company Product Phase  
Bayer HealthCare Pharmaceuticals with Novartis Betaferon / Betaseron (interferon beta- 1b) M Multiple Sclerosis
Questcor Pharmaceuticals Inc H.P. Acthar M Multiple Sclerosis
AutoImmune Inc MBP8298 III Multiple Sclerosis
Genentech Inc Rituxan III Multiple Sclerosis
Asphelia Pharmaceuticals, Inc. ASP1002 II Multiple Sclerosis
Isis Pharmaceuticals Inc ATL1102 II Multiple Sclerosis
Bayhill Therapeutics Inc BHT3009 II Multiple Sclerosis
MediciNova Inc MN166 II Multiple Sclerosis
Genentech Inc R1594 II Multiple Sclerosis
Facet Biotech Corporation Zenapax II Multiple Sclerosis

Myasthenia Gravis

Myasthenia Gravis is a chronic neuromuscular disease that leads to fluctuating weakness and fatigue. The waxing-and-waning weakness of muscles, worsening with use and improving with rest, is a hallmark of this particular disease. Myasthenia gravis is caused by a defect in the transmission of nerve impulses to muscles. It is a lesser known disorder and is estimated to affect about 14 people per 100,000 in the U.S.

Company Product Phase  
Valeant Pharmaceuticals International Mestinon M Myasthenia Gravis
Valeant Pharmaceuticals International Prostigmin M Myasthenia Gravis
Impax Laboratories Inc Pyridostigmine bromide M Myasthenia Gravis
Watson Pharmaceuticals Inc Pyridostigmine bromide M Myasthenia Gravis
Valeant Pharmaceuticals International Tensilon M Myasthenia Gravis

Obsessive Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a potentially disabling anxiety disorder. A person who has OCD has intrusive and unwanted thoughts and repeatedly performs tasks to get rid of the thoughts. The effects of OCD range from mild to severe.

Company Product Phase  
Jazz Pharmaceuticals Luvox M Obsessive-Compulsive Disorder
Jazz Pharmaceuticals Luvox CR M Obsessive-Compulsive Disorder