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Teeth are crucial to both our nutritional intake and to our identity. Every time we look in the mirror we see our teeth shining back at us, sometimes crooked, sometimes straight, and hopefully healthy. Unfortunately, as we age or become a little less meticulous with our cleaning habits, our teeth and gums may begin to have problems. Cavities and gum disease are two of the most common dental concerns. We can, however, work to prevent these two common problems by brushing and flossing regularly and avoiding foods high in sugars.
Caries
Dental caries is an infectious disease which damages the structures of teeth. Tooth decay or cavities are consequences of caries. If left untreated, the disease can lead to pain, tooth loss, infection and, in severe cases, death of the tooth.
| Company | Product | Phase | |
| Valeant Pharmaceuticals International | Fluossen | M | Caries |
| Planet Biotechnology Inc. | CaroRx | II | Caries |
Dental Pain
Dental pain is caused due to cavity in teeth and gum disease.
| Company | Product | Phase | |
| Lee Pharmaceuticals | Cankaid | M | Dental Pain |
| Watson Pharmaceuticals Inc | Triamcinolone Acet Dental Paste | M | Dental Pain |
Dental and Periodontal Problems
Trouble with teeth and gums often requires dental surgery to correct the problem. Gum disease, root canals and even everyday cavities can warrant surgery. Given the location of the surgery, however, patients can be left uncomfortable and in pain post operation. Currently most patients leave the dental office with only a few pain relievers and perhaps an anti-inflammatory to treat the post operative symptoms. There are several new drugs in development which seek to stimulate oral biological defenses and healing mechanisms which would result in less pain and complications after operations and restorative dental procedures.
| Company | Product | Phase | |
| Lee Pharmaceuticals | Perma-Grip | M | Dental Products |
| Lee Pharmaceuticals | Cankaid | M | Oral Care Product |
| Lee Pharmaceuticals | Vince | M | Oral Care Product |
| Acologix Inc | Dentonin | II | Dental Products |
| Anacor Pharmaceuticals, Inc. | AN0128 | II | Periodontitis |
