Gastroesophageal Reflux Disease (GERD)

Gastroesophageal reflux disease, known as GERD, is defined as chronic symptoms or mucosal damage produced by the abnormal reflux of gastric (stomach) contents into the esophagus. It is characterized by heartburn, esophageal inflammation, difficulty swallowing and chronic chest pain. Certain foods are known to exacerbate GERD: coffee, alcohol, Vitamin C, high fat foods, soft drinks, chocolate, peppermint and spicy foods, among many others. Patients should first change the foods they eat and ensure that they are exercising regularly. In more serious cases, drug therapies and surgery might be necessary.

Company Product Phase  
Santarus Inc Zegerid PA Gastroesophageal Reflux Disease
Watson Pharmaceuticals Inc Metoclopramide Hydrochloride M Gastroesophageal Reflux Disease
Impax Laboratories Inc Omeprazole M Gastroesophageal Reflux Disease
Watson Pharmaceuticals Inc Omeprazole M Gastroesophageal Reflux Disease
Watson Pharmaceuticals Inc Rulox Plus M Gastroesophageal Reflux Disease
Watson Pharmaceuticals Inc Sodium bicarbonate M Gastroesophageal Reflux Disease
Watson Pharmaceuticals Inc Papaya Enzyme M Gastroesophageal Reflux Disease
Ocera Therapeutics Inc AST120 II Gastroesophageal Reflux Disease
Depomed Inc DM3458 II Gastroesophageal Reflux Disease
Xenoport Inc XP19986 II Gastroesophageal Reflux Disease

Hemorrhoids

The term hemorrhoids refers to a condition in which the veins around the anus or lower rectum are swollen and inflamed. Hemorrhoids may result from straining to move stool. Other contributing factors include pregnancy, aging, chronic constipation or diarrhea, and anal intercourse. Hemorrhoids are either inside the anus—internal—or under the skin around the anus—external. Hemorrhoids are common in both men and women. About half of the population has hemorrhoids by age 50.

Company Product Phase  
Watson Pharmaceuticals Inc Hemorrhoidal suppositories M Hemorrhoids
Lee Pharmaceuticals Medicone M Hemorrhoids

Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by abdominal pain and changes in bowel habits which are not associated with any abnormalities seen on routine clinical testing. Lower abdominal pain, bloating associated with alteration of bowel habits and abdominal discomfort relieved with defecation are the most frequent symptoms. As many as 20 percent of the adult population, or one in five Americans, have symptoms of IBS, making it one of the most common disorders diagnosed by doctors. It occurs more often in women than in men, and it begins before the age of 35 in about 50 percent of people.

Company Product Phase  
Watson Pharmaceuticals Inc Dicyclomine hydrochloride M Irritable Bowel Syndrome
Valeant Pharmaceuticals International Formulex M Irritable Bowel Syndrome
Prometheus Laboratories, Inc. Lotronex M Irritable Bowel Syndrome
Neurocrine Biosciences Inc 876008 II Irritable Bowel Syndrome
Tioga Pharmaceuticals Inc Asimadoline II Irritable Bowel Syndrome

Nausea

Nausea is an unpleasant sensation, vaguely referred to the epigastrium and abdomen and often culminating in vomiting.

Company Product Phase  
Victory Pharma Inc MGX006 PA Nausea and Vomiting
Watson Pharmaceuticals Inc Dimenhydrinate M Nausea and Vomiting
Domperidone Amdl Inc M Nausea and Vomiting
Valeant Pharmaceuticals International Gastrosil M Nausea and Vomiting
Watson Pharmaceuticals Inc Kalmz M Nausea and Vomiting
Valeant Pharmaceuticals International Maxolon M Nausea and Vomiting
Watson Pharmaceuticals Inc Promethazine hydrochloride M Nausea and Vomiting