Ophthalmology & Optometry

As the saying goes, the eyes are the windows to the soul, but they also serve sthe important function of allowing us to look out on to the world around us and experience all there is to see. There are two fields of medicine that deal specifically with the eyes: ophthalmology and optometry. Ophthalmology deals primarily with diseases (such as pink eye) of the visual pathways between the eyes and brain. Optometry concerns itself with vision problems (such as farsightedness and nearsightedness). Many people visit an optometrist once a year to make sure that their vision is functioning properly and that their eyes are healthy. Ophthalmologists are generally only sought for the treatment of eye problems broader than those just concerning vision.

Cataract

A cataract is an ocular opacity, partial or complete, of one or both eyes, on or in the lens or capsule, especially an opacity impairing vision or causing blindness. Cataracts typically progress slowly to cause vision loss and are potentially blinding if untreated. By age 80, more than half of all Americans either have a cataract or have had cataract surgery.

Company Product Phase  
Chakshu Research C-KAD II Cataract

Dry Eye

Dry eye occurs when the tear ducts located in the eyes do not produce enough tears to adequately lubricate the eyes. It can lead to dry, itchy, stingy eyes that get worse as the day progresses. Causes include old age, arthritis, lupus, diabetes and other environmental factors such as weather. Dry eye is more common in women, especially after menopause.

Company Product Phase  
Watson Pharmaceuticals IncInSite Vision Inc AquaSite M Dry Eye Syndrome
Watson Pharmaceuticals Inc Artificial Tears M Dry Eye Syndrome
Allergan Inc Liquifilm M Dry Eye Syndrome
Optics Laboratory MiniDrops Eye Therapy M Dry Eye Syndrome
Watson Pharmaceuticals Inc Nature's Tears M Dry Eye Syndrome
Allergan Inc Optive M Dry Eye Syndrome
Allergan Inc Refresh Celluvisc M Dry Eye Syndrome
Allergan Inc Refresh Classic M Dry Eye Syndrome
Allergan Inc Refresh Contacts M Dry Eye Syndrome
Allergan Inc Refresh Dry Eye Therapy M Dry Eye Syndrome
Allergan Inc Refresh Dry Eye M Dry Eye Syndrome
Allergan Inc Refresh Lacrilube M Dry Eye Syndrome
Allergan Inc Refresh Liquigel M Dry Eye Syndrome
Allergan Inc Refresh Plus M Dry Eye Syndrome
Allergan Inc Refresh PM M Dry Eye Syndrome
Allergan Inc Refresh Redness Relief M Dry Eye Syndrome
Allergan Inc Refresh Tear M Dry Eye Syndrome
Allergan Inc Restasis M Dry Eye Syndrome
Allergan Inc Prolacria III Dry Eye Syndrome
Alacrity Biosciences, Inc. ALTY0501 II Dry Eye Syndrome
Allergan Inc Androgen Tear II Dry Eye Syndrome
ISTA Pharmaceuticals Inc Ecabet sodium II Dry Eye Syndrome
Nascent Pharmaceuticals Inc iDESTRIN II Dry Eye Syndrome
Allergan Inc Restasis X II Dry Eye Syndrome
SARcode Corporation SAR1118 II Dry Eye Syndrome
ISTA Pharmaceuticals Inc Xibrom II Dry Eye Syndrome

Eye Infections (include Conjunctivitis)

Eye infections are a moderate to severe infection caused by bacteria, fungi or viruses, which occurs either on the external surface of the eye or intraocularly with probable inflammation, visual impairment, or blindness. Two common eye infections are conjunctivitis and stye.

Company Product Phase  
InSite Vision Incorporated AzaSite PM Eye Diseases (General)
Allergan Inc Zymar X PA Conjunctivitis
ISTA Pharmaceuticals Inc T-Pred (tobramycin, prednisolone acetate) PA Ocular Inflammation
ISTA Pharmaceuticals Inc Xibrom QD PA Ocular Inflammation
Allergan Inc Acular M Conjunctivitis
Santen Inc Alamast M Conjunctivitis
Allergan Inc Alocril M Conjunctivitis
Valeant Pharmaceuticals International Antilerg M Conjunctivitis
InSite Vision Incorporated AzaSite M Conjunctivitis
InSite Vision Inc AzaSite M Conjunctivitis
InSite Vision Incorporated Besivance M Conjunctivitis
Allergan Inc Elestat M Conjunctivitis
Allergan Inc Ocuflox M Conjunctivitis
Santen Inc Quixin M Conjunctivitis
China Sky One Medical Inc Taurine M Conjunctivitis
Allergan Inc Zymar M Conjunctivitis
Allergan Inc Trivaris M Eye Diseases (General)
China Sky One Medical Inc Ofloxacin M Eye Infections
Valeant Pharmaceuticals International Polioftal M Eye Infections
Allergan Inc Polytrim M Eye Infections
Allergan Inc Acular LS M Ocular Inflammation
Allergan Inc Blephamide M Ocular Inflammation
Allergan Inc FML M Ocular Inflammation
Allergan Inc Pred Forte M Ocular Inflammation
ISTA Pharmaceuticals Inc Xibrom M Ocular Inflammation
Allergan Inc Alocril M Ophthalmic Itch
Valeant Pharmaceuticals International Ketopharm M Ophthalmic Itch
Allergan Inc Refresh Eye Itch Relief M Ophthalmic Itch
Allergan Inc Latisse M Ophthalmic Products
InSite Vision Incorporated AzaSite Plus III Conjunctivitis
NovaBay Pharmaceuticals, Inc. NVC422 II Conjunctivitis
ISTA Pharmaceuticals Inc Bepreve A Conjunctivitis
China Sky One Medical Inc Compound Zinc Sulfate A Conjunctivitis
China Sky One Medical Inc Tobramycin A Eye Infections
Allergan Inc Trivaris A Ocular Inflammation

Glaucoma

Glaucoma is a group of diseases that can damage the eye's optic nerve and result in vision loss and blindness. Glaucoma occurs when the normal fluid pressure inside the eyes slowly rises. However, with early treatment, a person can often protect the eyes against serious vision loss. It is the damage to the optic nerve that steals sight from people with glaucoma. Anyone can develop glaucoma, but it is five times more likely to occur in African Americans than in Caucasians.

Company Product Phase  
Allergan Inc Ganfort PA Glaucoma
Allergan Inc Lumigan X PA Glaucoma
Allergan Inc Alphagan P M Glaucoma
Allergan Inc Betagan M Glaucoma
Santen Inc Betimol M Glaucoma
Allergan Inc Combigan M Glaucoma
Valeant Pharmaceuticals International Glaucostat M Glaucoma
Valeant Pharmaceuticals International Glauteolol M Glaucoma
ISTA Pharmaceuticals Inc Istalol M Glaucoma
Allergan Inc Lumigan M Glaucoma
Solvay Luvox M Glaucoma
Allergan Inc Propine M Glaucoma
Allergan Inc AGN210669 II Glaucoma
Allergan Inc Brimonidine II Glaucoma
Chakshu Research C-KAD II Glaucoma
Allergan Inc IOP Lowering II Glaucoma
Allergan Inc PG analog II Glaucoma

Macular Degeneration

Most vision loss in people over the age of 55 is due to macular degeneration, a condition that affects 10 million Americans. Because the condition usually develops with age, it is generally referred to as Age-Related Macular Degeneration (ARMD). There are two types of ARMD: dry and wet. Dry ARMD occurs when the cells of the macula simply begin to break down. This process is usually slow and results in a blurred spot in the center of the field of vision. Wet ARMD is rarer than the dry form, but the results are much worse. It occurs when blood vessels behind the retina begin leaking blood and fluid behind the macula. As fluids fill the macula, one’s vision changes shape, causing straight lines to appear curved and the picture to blur.

Company Product Phase  
Miravant Medical Technologies Photrex (rostaporfin) PA Macular Degeneration
Genentech Inc Lucentis M Macular Degeneration
Gilead Sciences Inc Macugen M Macular Degeneration
Genentech, Inc. Lucentis III Macular Degeneration
CoMentis Inc ATG3 II Macular Degeneration
Allergan Inc Brimonidine tartrate II Macular Degeneration
Intradigm Corporation Cand5 II Macular Degeneration
Allergan Inc Dexamethasone with Anti-VEGF II Macular Degeneration
Genentech, Inc. Lucentis with Bromfenac II Macular Degeneration
Genentech Inc Lucentis with Visudyne II Macular Degeneration
Amgen Inc NT501 II Macular Degeneration
Quark Pharmaceuticals Inc RTP801i II Macular Degeneration
TargeGen Inc TG 100801 II Macular Degeneration
OXiGENE INC Zybrestat II Macular Degeneration

Macular Edema

Diabetic macular edema occurs when fluid and protein deposits collect on or under the macula, a key component of the retina responsible for high acuity vision, causing the macula to thicken and swell. The swelling may distort a person's central vision, as the macula is near the center of the retina at the back of the eyeball. Diabetic macular edema provides sharp, clear central vision that allows a person to see form, color and detail that is directly in the line of sight.

Company Product Phase  
Allergan Inc Laser Photocoagulation with Lucentis or Triamcinolone Acetonide III Diabetic Macular Edema
Genentech, Inc. Laser Photocoagulation with Lucentis or Triamcinolone Acetonide III Diabetic Macular Edema
Allergan Inc Posurdex III Diabetic Macular Edema
Allergan Inc Trivaris III Diabetic Macular Edema
Genentech, Inc. Lucentis with Triamcinolone acetonide III Diabetic Retinopathy
Genentech, Inc. Lucentis III Macular Edema
Allergan Inc Ozurdex III Macular Edema
MacuSight, Inc. MSR001 III Diabetic Macular Edema
Allergan Inc Posurdex with Laser III Diabetic Macular Edema
Quark Pharmaceuticals, Inc. RTP801i II Diabetic Macular Edema
Genentech, Inc. Lucentis II Diabetic Retinopathy

Photophobia

Photophobia is an abnormal visual intolerance of light. Photophobia is a fairly common symptom. For many people, photophobia is not due to any underlying disease. Severe photophobia may be associated with eye problems and cause severe eye pain even in relatively low light.

Company Product Phase  
Allergan Inc Acular PF M Photophobia

Retinal Vein Occlusion

Retinal vein occlusion is a blockage in the blood supply from the retina -- the light-sensitive tissue in the back of the eye. Veins of the retina can become blocked by a blood clot. Retinal vein occlusion also can occur when the retinal arteries put pressure on the retinal vein.

Company Product Phase  
Allergan Inc Posurdex PA Retinal Vein Occlusion
Genentech Inc Lucentis III Retinal Vein Occlusion
Allergan Inc Trivaris III Retinal Vein Occlusion
Genentech, Inc. Lucentis II Retinal Disorders
VitreoRetinal Technologies Inc Neurosolve II Retinal Disorders

Strabismus

Strabismus is the inability of one eye to attain binocular vision with the other because of imbalance of the muscles of the eyeball.

Company Product Phase  
Allergan Inc Botox M Strabismus

Ulcerative keratitis

Ulcerative keratitis is inflammation and ulceration of the cornea that often occurs in people who have connective tissue diseases such as rheumatoid arthritis.

Uveitis

Uveitis is an inflammation (swelling and irritation) of the the uvea. The uvea is the layer of the eye between the sclera and the retina. This layer includes the iris, ciliary body, and the choroid.

The uvea is very important because its many veins and arteries transport blood to the parts of the eye that are critical for vision.

Company Product Phase  
Allergan Inc Posurdex III Uveitis

Vitreous Hemorrhage

Bleeding from abnormal blood vessels growing on the retinam, vitreous hemorrhage occurs when portions of the retina receive inadequate blood supply, usually as the result of diabetes or blockage in a blood vessel. These areas produce a chemical which stimulates blood vessel growth. Unfortunately, the blood vessels that grow in response to this chemical are abnormal and they grow from the retina into the vitreous gel. They may bleed, known as a vitreous hemorrhage. Other common causes of vitreous hemorrhage are retinal tears and trauma.



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