The main function of the respiratory system (also known as the pulmonary system) is to supply the body with oxygen and rid it of carbon dioxide. This process also removes metabolic wastes and maintains the pH balances of the body. The organs involved are the airways, lungs, and muscles that mediate the movement of air into and out of the body. When you breathe, air comes in through the mouth and nose. It passes through the larynx, also known as the voice box, and enters the chest cavity through the trachea. The trachea then splits into two tubes called bronchi, each of which leads into a lung. The airways become progressively smaller and at the end are small sacs known as alveoli, which are surrounded by capillaries. The oxygen from the air moves into the alveoli. Carbon dioxide moves through the same path in the opposite direction and is exhaled.

Asthma

Asthma is a disease that affects the tubes that bring air to and from the lungs, called airways. The airway tubes, the trachea, bronchi and bronchioles, are surrounded by muscles that can contract, narrowing the tubes and thereby making it difficult to breathe. An asthma attack is an acute narrowing of the tubes in response to exposure to an allergen (like pollen, dust and animal dander), an irritant (like cigarette smoke, pollution and cold air) or even just exercise. When the airways become inflamed, they can also swell and aggravate or sensitize the person to asthma. It is not clear as to what causes people to be prone to asthma, but heredity and environmental factors play a role. According the NIH, nearly 22.9 million people have asthma.

Company Product Phase  
Valeant Pharmaceuticals International Budefarma M Asthma
DEY LP Cromolyn sodium M Asthma
Amphastar Pharmaceuticals Inc Epinephrine Mist CFC M Asthma
DEY LP Metaproterenol sulfate M Asthma
BioMarin Pharmaceutical Inc Orapred M Asthma
BioMarin Pharmaceutical Inc Orapred ODT M Asthma
Amphastar Pharmaceuticals, Inc. Primatene M Asthma
Genentech Inc Xolair M Asthma
DEY LP Zyflo M Asthma
DEY LP Zyflo CR M Asthma
AXM Pharma Inc Afaxin M Respiratory Diseases (General)
Valeant Pharmaceuticals International Budefarma M Respiratory Diseases (General)
Valeant Pharmaceuticals International Trimexine M Respiratory Diseases (General)
Genentech, Inc. Xolair (Liquid formulation) III Asthma
Medinox, Inc. Norathiol II Acute Respiratory Distress Syndrome
Aerovance, Inc. Aerovant II Asthma
Amgen Inc AMG317 II Asthma
Amgen Inc Enbrel II Asthma
Theravance Inc GSK159802 II Asthma
Theravance Inc GSK642444 with GW685698 II Asthma
Genentech Inc HAE1 II Asthma
APT Pharmaceuticals Inc. Hydroxychloroquine APT II Asthma
Inverseon, Inc. INV102 II Asthma
KaloBios Pharmaceuticals Inc KB002 II Asthma
KaloBios Pharmaceuticals, Inc. KB002 II Asthma
KaloBios Pharmaceuticals Inc KB003 II Asthma
Genentech, Inc. MILR1444A II Asthma
MediciNova Inc MN221 II Asthma
Theravance Inc TD3327 II Asthma
Genentech, Inc. TNX650 II Asthma

Bronchospasm

Bronchospasm is characterized by difficulty breathing due to the sudden constriction of the bronchi or bronchioles in the lungs. The constriction causes the airways to narrow and mucous production to increase, reducing the flow of air into the lungs and oxygen available to the body, which causes breathlessness, coughing and hypoxia. Bronchospasm usually accompanies asthma, chronic bronchitis, anaphylaxis and as a side effect of the drugs such as Pilocarpine or even aspirin.

Company Product Phase  
DEY LP AccuNeb M Bronchospasm
Watson Pharmaceuticals Inc Albuterol M Bronchospasm
Amphastar Pharmaceuticals Inc Albuterol CFC M Bronchospasm
DEY LP Albuterol sulfate M Bronchospasm
Watson Pharmaceuticals Inc Albuterol sulfate M Bronchospasm
DEY L.P. DuoNeb M Bronchospasm
Auriga Laboratories Inc Extendryl PSE M Bronchospasm
DEY LP Ipratropium bromide M Bronchospasm
Watson Pharmaceuticals Inc Ipratropium bromide, Albuterol sulfate M Bronchospasm
DEY LP Metaproterenol sulfate M Bronchospasm
Impax Laboratories Inc Terbutaline sulfate M Bronchospasm